{"product_id":"black-magic-supply-cortibloc","title":"CORTIBLOC (MAXIMUM CORTISOL BLOCKER)","description":"\u003ch3 class=\"PDq2pG_selectionAnchorContainer\"\u003eAdvanced Cortisol \u0026amp; Metabolic Support Formula\u003cspan class=\"PDq2pG_selectionAnchor\"\u003e\u003c\/span\u003e\n\u003c\/h3\u003e\n\u003cp\u003eStress is part of life—but supporting a healthy response to stress can make a difference in how you feel and perform. \u003cstrong\u003eBlack Magic Corti Block\u003c\/strong\u003e is a targeted two-ingredient formula featuring \u003cstrong\u003eKnotweed Extract standardized to 95% Emodin\u003c\/strong\u003e plus \u003cstrong\u003eBlack Pepper Fruit Extract standardized to 95% Piperine\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eDesigned to support a \u003cstrong\u003ebalanced cortisol response and healthy insulin function\u003c\/strong\u003e, Corti Block combines a concentrated botanical active with piperine to complement its absorption and bioavailability.*\u003c\/p\u003e\n\u003ch3\u003eWhy CortiBloc?\u003c\/h3\u003e\n\u003cp\u003eCortisol is an essential hormone involved in the body's stress response, energy metabolism, blood sugar regulation, and numerous other physiological processes. Corti Block was formulated to provide nutritional support for maintaining a healthy cortisol and metabolic response.*\u003c\/p\u003e\n\u003cp\u003eResearch on emodin has found that it can inhibit \u003cstrong\u003e11β-HSD1\u003c\/strong\u003e, an enzyme involved in converting inactive cortisone into active cortisol. These findings come largely from laboratory and animal research, so they should be described as mechanistic support rather than proof that this supplement lowers cortisol in humans. \u003cspan class=\"contents\"\u003e\u003cspan class=\"\"\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eKey Ingredients \u0026amp; Benefits\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eKnotweed Extract (Polygonum cuspidatum) — 250 mg\u003c\/strong\u003e\u003cbr\u003eStandardized to contain \u003cstrong\u003e95% Emodin\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEmodin is a naturally occurring bioactive compound found in \u003cem\u003ePolygonum cuspidatum\u003c\/em\u003e. It has been studied for several metabolic pathways and provides the foundation of the Corti Block formula.\u003c\/p\u003e\n\u003cp\u003ePotential benefits include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cem\u003eSupports a healthy cortisol response:\u003c\/em\u003e* Emodin has demonstrated activity against 11β-HSD1, an enzyme involved in local cortisol production. \u003cspan class=\"contents\"\u003e\u003cspan class=\"\"\u003e\u003c\/span\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eSupports healthy insulin function and glucose metabolism:\u003c\/em\u003e* Preclinical research has investigated emodin's effects on insulin-stimulated glucose uptake and other pathways involved in glucose metabolism. \u003cspan class=\"contents\"\u003e\u003cspan class=\"\"\u003e\u003c\/span\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eSupports metabolic health:\u003c\/em\u003e* Emodin continues to be studied for its effects on multiple pathways involved in metabolic function. \u003cspan class=\"contents\"\u003e\u003cspan class=\"\"\u003e\u003c\/span\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eProvides botanical antioxidant support:\u003c\/em\u003e* \u003cem\u003ePolygonum cuspidatum\u003c\/em\u003e contains numerous naturally occurring bioactive compounds that have been investigated for their biological activity. \u003cspan class=\"contents\"\u003e\u003cspan class=\"\"\u003e\u003c\/span\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eBlack Pepper Fruit Extract — 25 mg\u003c\/strong\u003e\u003cbr\u003eStandardized to contain \u003cstrong\u003e95% Piperine\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePiperine is the primary bioactive compound found in black pepper and is commonly incorporated into advanced supplement formulas as a \u003cstrong\u003ebioavailability enhancer\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003ePotential benefits include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cem\u003eEnhances bioavailability:\u003c\/em\u003e* Piperine can influence intestinal and hepatic metabolism of certain compounds, potentially increasing their absorption and exposure. \u003cspan class=\"contents\"\u003e\u003cspan class=\"\"\u003e\u003c\/span\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eComplements emodin specifically:\u003c\/em\u003e* In an animal pharmacokinetic study, piperine significantly increased emodin exposure and inhibited its glucuronidation, although this has not yet established the same effect in humans. \u003cspan class=\"contents\"\u003e\u003cspan class=\"\"\u003e\u003c\/span\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eAntioxidant and metabolic support:\u003c\/em\u003e* Piperine has also been studied for antioxidant, inflammatory, and metabolic-health effects. \u003cspan class=\"contents\"\u003e\u003cspan class=\"\"\u003e\u003c\/span\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSimple. Concentrated. Purpose-Driven.\u003c\/h3\u003e\n\u003cp\u003eCorti Block doesn't rely on an oversized ingredient panel. Each capsule delivers:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e250 mg Knotweed Extract (95% Emodin)\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003e25 mg Black Pepper Extract (95% Piperine)\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003e120 Capsules Per Bottle\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003e120 Servings\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWith \u003cstrong\u003eone capsule per serving\u003c\/strong\u003e, Corti Block makes it easy to add targeted cortisol and metabolic support to your daily supplement routine.*\u003c\/p\u003e\n\u003ch3\u003eBLACK MAGIC CORTIBLOC BENEFITS*\u003c\/h3\u003e\n\u003cp\u003e✓ Promotes a balanced cortisol response\u003cbr\u003e✓ Supports healthy insulin function\u003cbr\u003e✓ Supports healthy glucose metabolism\u003cbr\u003e✓ Supports overall metabolic health\u003cbr\u003e✓ Provides antioxidant support\u003cbr\u003e✓ Features highly concentrated 95% Emodin\u003cbr\u003e✓ Includes 95% Piperine for bioavailability support\u003cbr\u003e✓ Convenient one-capsule serving\u003cbr\u003e✓ 120 servings per bottle\u003c\/p\u003e","brand":"Black Magic Supply","offers":[{"title":"Default Title","offer_id":44474220576867,"sku":"Black-Magic-Supply-Cortibloc-1-Bottle","price":49.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0074\/2264\/0197\/files\/ChatGPT_Image_Sep_9_2026_02_17_58_PM.png?v=1788977907","url":"https:\/\/www.blackmagicsupps.com\/products\/black-magic-supply-cortibloc","provider":"Black Magic Supply","version":"1.0","type":"link"}